Methyl iodide → HCID 20248961, Verbindung

HRID 1285334Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1285334
[CH2:1]([N:8]1[CH2:14][C:12](=[O:13])[NH:11][C:9]1=[S:10])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[I:15][CH3:16]>CO>[IH:15].[CH2:1]([N:8]1[CH2:14][C:12](=[O:13])[N:11]=[C:9]1[S:10][CH3:16])[C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1

Komponenten

4

Edukt 2

HCID 6328Methyl iodideHCID 53685104-Imidazolidinone, 1-(phenylmethyl)-2-thioxo-

Produkt 1

HCID 20248961HCID 20248961, Verbindung

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 887MethanolLösungsmittel

Versuchsvorschrift

1-Benzyl-2-thiohydantoin (8.07 g), iodomethane (10 ml) and methanol (50 ml) were warmed at 40°-42° C. for 8 hours. The reaction mixture was evaporated under reduced pressure, the residue was washed with diethyl ether and recrystallised from methanol-ethanol to give 1-benzyl-2-methylthio-2-imidazolin-4-one hydroiodide (4.86 g) m.p. 185°-190° C., as an impure light-buff coloured solid which was taken on to the next stage.

Aufarbeitung

  1. customThe reaction mixture was evaporated under reduced pressure
  2. washthe residue was washed with diethyl ether
  3. customrecrystallised from methanol-ethanol

Quellen und Nachweise

ORD-Eintrag
ord-323d82de3baf487685aa77e1d8b8ca82
Quelldatensatz
uspto-grants-1986_01
Patentnummer
US04567176

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