Sec-Butylamine → HCID 21503679, Verbindung
Reaktionsgleichung
[C:1]([C:9]1[C:10](OCC)=[C:11]2[CH:17]=[N:16][N:15]([CH2:18][C:19]3[O:20][CH:21]=[CH:22][CH:23]=3)[C:12]2=[N:13][CH:14]=1)(=[O:8])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[CH:27]([NH2:31])([CH2:29][CH3:30])[CH3:28]>>[C:1]([C:9]1[C:10]([NH:31][CH:27]([CH2:29][CH3:30])[CH3:28])=[C:11]2[CH:17]=[N:16][N:15]([CH2:18][C:19]3[O:20][CH:21]=[CH:22][CH:23]=3)[C:12]2=[N:13][CH:14]=1)(=[O:8])[C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1Komponenten
3
Versuchsvorschrift
34.7 g. of 5-benzoyl-4-ethoxy-1-(2-furanyl)methyl-1H-pyrazolo[3,4-b]pyridine (0.1 mol.) is refluxed for 10 hours with 50 ml. of sec. butylamine. The excess amine is removed in vacuo and the residue recrystallized from methanol to obtain 5-benzoyl-4-sec.butylamino-1-(2-furanyl)methyl-1H-pyrazolo[3,4-b]pyridine, yield 31 g. (83%), m.p. 112°-114° (methanol).
Aufarbeitung
- customThe excess amine is removed in vacuo
- customthe residue recrystallized from methanol
Quellen und Nachweise
- ORD-Eintrag
- ord-81ba7bbc55a448cb8256bbba990ddbc4