HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
N-methylhydroxylamine hydrochloride → alpha-(1-Methyl-2-nitroimidazole-5-yl)-N-methylnitrone
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | N-methylhydroxylamine hydrochloride | HCID 77906 | — |
| Edukt | 1-Methyl-2-nitro-1H-imidazole-5-carboxaldehyde | HCID 100390 | — |
| Edukt | Sodium Bicarbonate | HCID 516892 | — |
| Lösungsmittel | Ethanol | HCID 702 | — |
| Produkt | alpha-(1-Methyl-2-nitroimidazole-5-yl)-N-methylnitrone | HCID 325650 | — |
Reaktionsschritte
A mixture of 0.250 g. of 1-methyl-2-nitro-5-imidazolecarboxaldehyde, 0.150 g. of N-methylhydroxylamine hydrochloride and 0.150 g. of sodium bicarbonate is refluxed in 80 ml. of anhydrous ethanol for 2 hours and after filtration is concentrated to small volume. The title compound crystallizes on cooling. Yield: 0.24 g, m.p. 208°-209° C.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US03987053 |
| Quelldatensatz | uspto-grants-1976_10 |
| ORD ID | ord-2752f34f108c41339ac7b1ed499c1c8c |
| Quellennotiz | uspto-grants-1976_10 |