HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
methyl 4-(1-methyl-1H-indol-3-yl)butanoate → 4-(2-oxo-2,3-dihydro-1H-indol-3-yl)butanoic acid
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | methyl 4-(1-methyl-1H-indol-3-yl)butanoate | HCID 3345143 | — |
| Edukt | DMSO HCl | HCID 12206146 | — |
| Produkt | 4-(2-oxo-2,3-dihydro-1H-indol-3-yl)butanoic acid | HCID 2764088 | — |
| Produkt | 4-(1-Methyl-2-oxo-3-indolinyl)butanoic acid | HCID 14956204 | — |
Reaktionsschritte
Reaction of the ester [II: R1 =R3 =H, R2 =(CH2)3COOMe, R3 =Me] with DMSO/HCl as above gave crude 4-(1-methyl-2-oxo-3-indolinyl)butanoic acid [III: R1 =R3 =H, R2 =(CH2)3COOMe, R3 =Me] (0.84 g, 91% yield) as a brown oil.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US05464861 |
| Quelldatensatz | uspto-grants-1995_11 |
| ORD ID | ord-fb7e125a62ab4aadb911826a54a70950 |
| Quellennotiz | uspto-grants-1995_11 |