Hydrochloric Acid → 9-Methyltetrazolo[1,5-a]quinoxaline

HRID 1288325Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1288325
Cl[C:2]1[CH:3]=[N:4][C:5]2[C:10]([N:11]=1)=[C:9]([CH3:12])[CH:8]=[CH:7][CH:6]=2.[N-:13]=[N+:14]=[N-:15].[Na+].Cl>C(O)C>[CH3:12][C:9]1[CH:8]=[CH:7][CH:6]=[C:5]2[C:10]=1[N:11]1[N:13]=[N:14][N:15]=[C:2]1[CH:3]=[N:4]2

Komponenten

5

Edukt 3

HCID 313Hydrochloric AcidHCID 33557Sodium AzideHCID 215049212-Chloro-8-methylquinoxaline

Produkt 1

HCID 215048979-Methyltetrazolo[1,5-a]quinoxaline

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 702EthanolLösungsmittel

Versuchsvorschrift

The crude 3-chloro-5-methylquinoxaline obtained in the step above was stirred for 3 hours at reflux temperature in 75 ml. of ethanol containing 1.8 g. of sodium azide and 20 ml. of 1N HCl. When the reaction mixture was cooled, the product precipitated as needles. Recrystallization of the product from ethanol produced highly purified 9-methyltetrazolo[1,5-a]quinoxaline, m.p. 166°-68° C. The product was identified by NMR analysis and by elemental microanalysis.______________________________________ Theoretical FoundC 58.37% 58.11%H 3.81 3.98N 37.82 37.60______________________________________

Aufarbeitung

  1. temperatureat reflux temperature in 75 ml
  2. temperatureWhen the reaction mixture was cooled
  3. customthe product precipitated as needles
  4. customRecrystallization of the product from ethanol

Quellen und Nachweise

ORD-Eintrag
ord-a6bd63ae652744e8b570c1052848e750
Quelldatensatz
uspto-grants-1976_10
Patentnummer
US03987196

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