HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Veratrylamine → 4-bromo-6-[3-(4-chlorophenyl)-3-hydroxypropyloxy]-5-(3,4-dimethoxybenzylamino)-3(2H)pyridazinone
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Veratrylamine | HCID 79832 | — |
| Edukt | 4,5-dibromo-6-[3-(4-chlorophenyl)-3-hydroxypropyloxy]-3(2H)pyridazinone | HCID 54023701 | — |
| Lösungsmittel | Triethylamine | HCID 8471 | — |
| Produkt | 4-bromo-6-[3-(4-chlorophenyl)-3-hydroxypropyloxy]-5-(3,4-dimethoxybenzylamino)-3(2H)pyridazinone | HCID 15390859 | 68,5% |
Reaktionsschritte
From 300 mg of 4,5-dibromo-6-[3-(4-chlorophenyl)-3- hydroxypropyloxy]-3(2H)pyridazinone, 228 mg of 3,4-dimethoxybenzylamine and 69 mg of triethylamine, 246 mg of the title compound was prepared in the same manner as in Example 1, as white crystals having a melting point of 190°-196° C.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US05750523 |
| Quelldatensatz | uspto-grants-1998_05 |
| ORD ID | ord-e9a8ce52d8c641d4981556457c6d7030 |
| Quellennotiz | uspto-grants-1998_05 |