Methyl 3-(4-aminophenyl)propanoate → HCID 10642582, Verbindung

HRID 1290986

Reaktionsgleichung

Reaktionsgleichung von HRID 1290986
C(C1C=CC2OC(C(O)=O)=CC=2C=1)#[N:2].NC1C=CC(CCC(OC)=O)=CC=1.[C:28]([C:30]1[CH:31]=[CH:32][C:33]2[O:37][C:36]([C:38]([NH:40][C:41]3[CH:46]=[CH:45][C:44]([CH2:47][CH2:48][C:49]([O:51][CH3:52])=[O:50])=[CH:43][CH:42]=3)=[O:39])=[CH:35][C:34]=2[CH:53]=1)#[N:29]>>[C:28]([C:30]1[CH:31]=[CH:32][C:33]2[O:37][C:36]([C:38]([NH:40][C:41]3[CH:46]=[CH:45][C:44]([CH2:47][CH2:48][C:49]([O:51][CH3:52])=[O:50])=[CH:43][CH:42]=3)=[O:39])=[CH:35][C:34]=2[CH:53]=1)(=[NH:2])[NH2:29]

Komponenten

4

Edukt 3

HCID 417374Methyl 3-(4-aminophenyl)propanoateHCID 102360545-cyanobenzofuran-2-carboxylic AcidHCID 10497906Methyl 3-[4-[(5-cyano-2-benzofuranyl)carbonylamino]phenyl]propionate

Produkt 1

HCID 10642582HCID 10642582, Verbindung

Versuchsvorschrift

In the same manner as in Example 1 (2), 5-cyano-2-benzofurancarboxylic acid (200 mg, 1.07 mmol) and methyl 3-(4-aminophenyl)propionate (211 mg, 1.18 mmol) were condensed to quantitatively give 371 mg of methyl 3-[4-[(5-cyano-2-benzofuranyl)carbonylamino]phenyl]propionate as a yellow solid.

Quellen und Nachweise

ORD-Eintrag
ord-ae363392784f46c4980764bde5f0180d
Quelldatensatz
uspto-grants-1998_05
Patentnummer
US05753670

Verknüpfte Notizen

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