Ammonia → N-BENZYLIDENE-2-PROPYNYLAMINE

HRID 1292541Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1292541
CS(O[CH2:6][C:7]#[CH:8])(=O)=O.[CH:9](=O)[C:10]1[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=1.[NH3:17]>C1(C)C=CC=CC=1>[CH:9](=[N:17][CH2:6][C:7]#[CH:8])[C:10]1[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=1

Komponenten

5

Edukt 3

HCID 222AmmoniaHCID 240BenzaldehydeHCID 305925propargyl mesylate

Produkt 1

HCID 4172560N-BENZYLIDENE-2-PROPYNYLAMINEAusbeute 85 %

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 1140TolueneLösungsmittel

Versuchsvorschrift

Propargyl methanesulfonate (31.6 g, 0.236 mol) and benzaldehyde (31.9 g, 0.3 mol) were dissolved in 103 g of toluene and an aqueous 28% ammonia solution (122 g, 2 mol) was added dropwise at 21° C. over 8 hours to the solution, followed by stirring at the same temperature for 15 hours. After separating, the resultant organic phase was washed with water and concentrated until the weight became 57.3 g to obtain a toluene solution containing 28.6 g (yield: 85%) of N-benzylidene-2-propynylamine.

Aufarbeitung

  1. customAfter separating
  2. washthe resultant organic phase was washed with water
  3. concentrationconcentrated until the weight
  4. customto obtain a toluene solution

Quellen und Nachweise

ORD-Eintrag
ord-5ddd84546c0b4594a50cd7d2ef279fcb
Quelldatensatz
uspto-grants-1998_05
Patentnummer
US05756769

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