Dimethylformamide diethylacetal → N,N-Dimethyl-2-(3-nitropyridin-4-yl)ethenamine

HRID 129466

Reaktionsgleichung

Reaktionsgleichung von HRID 129466
[CH3:1][C:2]1[CH:7]=[CH:6][N:5]=[CH:4][C:3]=1[N+:8]([O-:10])=[O:9].C(O[CH:14](OCC)[N:15]([CH3:17])[CH3:16])C>>[CH3:14][N:15](/[CH:17]=[CH:1]/[C:2]1[CH:7]=[CH:6][N:5]=[CH:4][C:3]=1[N+:8]([O-:10])=[O:9])[CH3:16]

Komponenten

3

Edukt 2

HCID 70913Dimethylformamide diethylacetalHCID 5218284-Methyl-3-nitropyridine

Produkt 1

HCID 11063279N,N-Dimethyl-2-(3-nitropyridin-4-yl)ethenamine

Versuchsvorschrift

Commercially available 4-methyl-3-nitropyridine is condensed with N,N-dimethylformamide diethyl acetal to provide E-4-[2-(N,N-dimethylamino)-1-ethenyl]-3-nitropyridine, which is then subjected to catalytic hydrogenation to give 6-azaindole.

Quellen und Nachweise

ORD-Eintrag
ord-e0d7c6e2ad1f47c78b58f92fa658c027
Quelldatensatz
uspto-grants-1995_11
Patentnummer
US05468757

Verknüpfte Notizen

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