3-Isoxazolamine → [1-(5-tert-Butyl-isoxazol-3-ylcarbamoyl)-ethyl]-carbamic acid tert-butyl ester
Reaktionsgleichung
[C:1]([O:5][C:6](=[O:24])[NH:7][CH:8]([C:12](=[O:23])[NH:13][C:14]1[CH:18]=[C:17]([C:19]([CH3:22])([CH3:21])[CH3:20])[O:16][N:15]=1)[CH2:9]CC)([CH3:4])([CH3:3])[CH3:2].NC1C=CON=1>>[C:1]([O:5][C:6](=[O:24])[NH:7][CH:8]([C:12](=[O:23])[NH:13][C:14]1[CH:18]=[C:17]([C:19]([CH3:22])([CH3:21])[CH3:20])[O:16][N:15]=1)[CH3:9])([CH3:3])([CH3:2])[CH3:4]Komponenten
3
Versuchsvorschrift
Prepared by the analogous method for the preparation of [1-(5-tert-butyl-isoxazol-3-ylcarbamoyl)butyl]-carbamic acid tert-butyl ester, starting with an appropriate amino-isoxazole (1a-b) together with an appropriate N-t-BOC-amino acid methyl or ethyl ester.
Quellen und Nachweise
- ORD-Eintrag
- ord-9694e71e1dbf485283421246a81b7d07
- Quelldatensatz
- uspto-grants-2007_07
- DOI