Methylhydrazine → 3-(4-Chlorophenyl)-1-Methyl-1H-Pyrazol-5-Amine

Beteiligte Stoffe

Reaktionsschritte

A solution of 3-(4-Chloro-phenyl)-3-oxo-propionitrile (1.8 g, 10 mmol) and N-Methylhydrazine (1 mL, excess) in EtOH (30 mL) was stirred to reflux 3 hours. After cooling the precipitate was filtered off, to give the title compound (950 mg, 4.6 mmol) as white crystals in a 46% yield.

Herkunft & Nachweise