Triethyl phosphite → Diethyl (Methoxymethyl)phosphonate
Reaktionsgleichung
C([O:3][P:4]([O:8][CH2:9][CH3:10])[O:5][CH2:6][CH3:7])C.[CH3:11][O:12][CH2:13]Br>>[CH3:11][O:12][CH2:13][P:4](=[O:3])([O:5][CH2:6][CH3:7])[O:8][CH2:9][CH3:10]Komponenten
3
Versuchsvorschrift
To a sample of 17.90 mL (0.104 mol) of triethylphosphite at -78° C. under argon was added dropwise 8.50 mL (0.104 mol) of bromomethyl methyl ether. The mixture slowly warmed to RT and stirred for 24 h, when it was fractionally distilled (bp 100° C., 5 mm) to provide 16.22 g (98%) of title compound as a pale yellow oil.
Aufarbeitung
- distillationwhen it was fractionally distilled (bp 100° C., 5 mm)
Quellen und Nachweise
- ORD-Eintrag
- ord-b9f3818a0f834bd892592a8c40680371
- Quelldatensatz
- uspto-grants-1995_11
- Patentnummer
- US05470845
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