Triethyl phosphite → Diethyl (Methoxymethyl)phosphonate

HRID 129797

Reaktionsgleichung

Reaktionsgleichung von HRID 129797
C([O:3][P:4]([O:8][CH2:9][CH3:10])[O:5][CH2:6][CH3:7])C.[CH3:11][O:12][CH2:13]Br>>[CH3:11][O:12][CH2:13][P:4](=[O:3])([O:5][CH2:6][CH3:7])[O:8][CH2:9][CH3:10]

Komponenten

3

Edukt 2

HCID 31215Triethyl phosphiteHCID 83093Bromomethyl methyl ether

Produkt 1

HCID 11658394Diethyl (Methoxymethyl)phosphonateAusbeute 98 %

Versuchsvorschrift

To a sample of 17.90 mL (0.104 mol) of triethylphosphite at -78° C. under argon was added dropwise 8.50 mL (0.104 mol) of bromomethyl methyl ether. The mixture slowly warmed to RT and stirred for 24 h, when it was fractionally distilled (bp 100° C., 5 mm) to provide 16.22 g (98%) of title compound as a pale yellow oil.

Aufarbeitung

  1. distillationwhen it was fractionally distilled (bp 100° C., 5 mm)

Quellen und Nachweise

ORD-Eintrag
ord-b9f3818a0f834bd892592a8c40680371
Quelldatensatz
uspto-grants-1995_11
Patentnummer
US05470845

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