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HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
HRID 131672Erstellt: 24. Oktober 2026

4-[2-methyl-5-(5-methyl-1,3,4-oxadiazol-2-yl)phenyl]benzoic Acid → 2'-Methyl-5'-(5-methyl-1,3,4-oxadiazol-2-yl)-N-(3-[(3-phenylureido)methyl]phenyl}-1,1'-biphenyl-4-carboxamide

https://huagongshe.com/de/reaction/131672

Reaktionsgleichung

Beteiligte Stoffe

RolleNameHCIDEinwaage
Edukt4-[2-methyl-5-(5-methyl-1,3,4-oxadiazol-2-yl)phenyl]benzoic AcidHCID 11220119—
EduktN-(3-aminobenzyl)-N'-phenylureaHCID 59190887—
Produkt2'-Methyl-5'-(5-methyl-1,3,4-oxadiazol-2-yl)-N-(3-[(3-phenylureido)methyl]phenyl}-1,1'-biphenyl-4-carboxamideHCID 10229641—

Reaktionsschritte

2′-Methyl-5′-(5-methyl-1,3,4-oxadiazol-2-yl)-N-{3-[(3-phenylureido)methyl]phenyl}-1,1′-biphenyl-4-carboxamide was prepared from 2′-methyl-5′-(5-methyl-1,3,4-oxadiazol-2-yl)-1,1′-biphenyl-4-carboxylic acid and N-(3-aminobenzyl)-N′-phenylurea using method J. NMR; δH [2H6]—DMSO 10.36,(1H, b), 8.57,(1H, s), 8.06,(2H, d), 7.90,(1H, dd), 7.78,(2H, m), 7.69,(1H, dd), 7.57,(3H, m), 7.39,(3H, m), 7.21,(2H, m), 7.05,(1H, d), 6.62,(1H, t), 4.31,(2H, d), 2.57,(3H, s), 2.33,(3H, s). LCMS; retention time 3.55 min, MH+ 518.

Herkunft & Nachweise

DOI10.6084/m9.figshare.5104873.v1
PatentnummerUS07384963B2
Quelldatensatzuspto-grants-2008_06
ORD IDord-2b9e7fc1a92849c79815f7a82b4e5c7b
Quellennotizuspto-grants-2008_06