HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
2-Aminothiazole → 1-[2-(2-Methoxy-benzoyl)-5-methyl-phenyl]-3-thiazol-2-yl-urea
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 2-Aminothiazole | HCID 2155 | — |
| Edukt | 4-Methylanthranilic acid | HCID 75316 | — |
| Edukt | (2-Amino-4-methyl-phenyl)-(2-methoxy-phenyl)-methanone | HCID 66998866 | — |
| Produkt | 1-[2-(2-Methoxy-benzoyl)-5-methyl-phenyl]-3-thiazol-2-yl-urea | HCID 59732938 | 70% |
| Produkt | (2-Amino-4-methyl-phenyl)-(2-methoxy-phenyl)-methanone | HCID 66998866 | 30% |
Reaktionsschritte
(2-Amino-4-methyl-phenyl)-(2-methoxy-phenyl)-methanone (723 g, 30%) was prepared from 2-amino-4-methyl-benzoic acid (1.51 g, 10 mmol) following the general procedure S. 1-[2-(2-methoxy-benzoyl)-5-methyl-phenyl]-3-thiazol-2-yl-urea (129 mg, 70%) was prepared from (2-amino-4-methyl-phenyl)-(2-methoxy-phenyl)-methanone (121 mg, 0.5 mmol) and 2-aminothiazole (0.060 g, 0.6 mmol) following the general procedure D.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US07384967B2 |
| Quelldatensatz | uspto-grants-2008_06 |
| ORD ID | ord-ade1a85adb924061b6e835d2696efdc5 |
| Quellennotiz | uspto-grants-2008_06 |