2-Hydroxy-N,N-dimethylbenzamide → 5-(2-Dimethylcarbamoyl-phenoxy)-6-(4-methanesulfonyl-phenoxy)-2-pyridin-2-yl-1H-benzimidazole

HRID 13235

Reaktionsgleichung

Reaktionsgleichung von HRID 13235
C([O:3][C:4]([C:6]1[CH:38]=[CH:37][CH:36]=[CH:35][C:7]=1[O:8][C:9]1[C:23]([O:24][C:25]2[CH:30]=[CH:29][C:28]([S:31]([CH3:34])(=[O:33])=[O:32])=[CH:27][CH:26]=2)=[CH:22][C:12]2[NH:13][C:14]([C:16]3[CH:21]=[CH:20][CH:19]=[CH:18][N:17]=3)=[N:15][C:11]=2[CH:10]=1)=O)C.[CH3:39][N:40](C)[C:41](=O)C1C=CC=CC=1O>>[CH3:39][N:40]([CH3:41])[C:4]([C:6]1[CH:38]=[CH:37][CH:36]=[CH:35][C:7]=1[O:8][C:9]1[C:23]([O:24][C:25]2[CH:30]=[CH:29][C:28]([S:31]([CH3:34])(=[O:33])=[O:32])=[CH:27][CH:26]=2)=[CH:22][C:12]2[NH:13][C:14]([C:16]3[CH:21]=[CH:20][CH:19]=[CH:18][N:17]=3)=[N:15][C:11]=2[CH:10]=1)=[O:3]

Komponenten

3

Edukt 2

HCID 745002-Hydroxy-N,N-dimethylbenzamideHCID 231451405-(2-Ethoxycarbonyl-phenoxy)-6-(4-methanesulfonyl-phenoxy)-2-pyridin-2-yl-1H-benzimidazole

Produkt 1

HCID 231453525-(2-Dimethylcarbamoyl-phenoxy)-6-(4-methanesulfonyl-phenoxy)-2-pyridin-2-yl-1H-benzimidazole

Versuchsvorschrift

The entitled compound was obtained in the same method as in Example 14 or in accordance with the method or by combining it with an ordinary method but using 4-fluoro-5-(4-methanesulfonyl-phenoxy)-2-nitro-phenylamine obtained in Example 14 and 2-hydroxybenzoic acid dimethylamide in order.

Aufarbeitung

  1. customThe entitled compound was obtained in the same method as in Example 14 or in accordance with the method

Quellen und Nachweise

ORD-Eintrag
ord-add36451338c4ee9a2bb43c5f598956f
Quelldatensatz
uspto-grants-2010_06
Patentnummer
US07728025B2

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