HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
5-(3-Chloro-propoxy)-1H-indole-2-carboxylic acid ethyl ester → 5-(3-Chloro-propoxy)-1H-indole-2-carboxylic acid
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 5-(3-Chloro-propoxy)-1H-indole-2-carboxylic acid ethyl ester | HCID 45112356 | — |
| Edukt | [5-Hydroxy-1-(2,2,2-trifluoro-ethyl)-1H-indol-2-yl]-morpholin-4-yl-methanone | HCID 67527268 | — |
| Produkt | 5-(3-Chloro-propoxy)-1H-indole-2-carboxylic acid | HCID 67526619 | — |
Reaktionsschritte
In analogy to the procedure described for the synthesis of intermediate 1, step 3, the title compound was synthesized from 5-(3-chloro-propoxy)-1H-indole-2-carboxylic acid ethyl ester (example 4, step 1). The title compound was obtained in 98% yield as white solid. MS (m/e): 252.9 (M−H−, 100%).
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US07388095B2 |
| Quelldatensatz | uspto-grants-2008_06 |
| ORD ID | ord-1f648f46653546e88c7464e7232e9449 |
| Quellennotiz | uspto-grants-2008_06 |