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HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
HRID 132826Erstellt: 25. Oktober 2026

(5-hydroxy-1H-indol-2-yl)-morpholin-4-yl-methanone → {5-[3-(3-Aza-bicyclo[3.1.0]hex-3-yl)-propoxy]-1H-indol-2-yl}-morpholin-4-yl-methanone

https://huagongshe.com/reaction/132826

Reaktionsgleichung

Beteiligte Stoffe

RolleNameHCIDEinwaage
Edukt(5-hydroxy-1H-indol-2-yl)-morpholin-4-yl-methanoneHCID 44185244—
Edukt3-(3-Azabicyclo[3.1.0]hexan-3-yl)propan-1-olHCID 67527519—
Produkt{5-[3-(3-Aza-bicyclo[3.1.0]hex-3-yl)-propoxy]-1H-indol-2-yl}-morpholin-4-yl-methanoneHCID 16754253—

Reaktionsschritte

In analogy to the procedure described for the synthesis of example 1, step 1, the title compound was synthesized from (5-hydroxy-1H-indol-2-yl)-morpholin-4-yl-methanone (example 5, step 3) and 3-(3-aza-bicyclo[3.1.0]hex-3-yl)-propan-1-ol (example 5, step 2). The title product was obtained in 49% yield as white solid. MS (m/e): 370.5 (MH+, 100%).

Herkunft & Nachweise

DOI10.6084/m9.figshare.5104873.v1
PatentnummerUS07388095B2
Quelldatensatzuspto-grants-2008_06
ORD IDord-3e3303021aa14bd39e263710560930e2
Quellennotizuspto-grants-2008_06