HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Trifluoroacetic acid → 2-(trifluoromethyl)-5H,6H,7H,8H-pyrido[4,3-d]pyrimidine
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Trifluoroacetic acid | HCID 6422 | — |
| Edukt | 6-(tert-Butoxycarbonyl)-2-(trifluoromethyl)-5,6,7,8-tetrahydropyrido[4,3-d]pyrimidine | HCID 69223721 | — |
| Lösungsmittel | Dichloromethane | HCID 6344 | — |
| Produkt | 2-(trifluoromethyl)-5H,6H,7H,8H-pyrido[4,3-d]pyrimidine | HCID 53471483 | — |
Reaktionsschritte
Reaction of the product from Step A above with trifluoroacetic acid in dichloromethane according to the procedure outlined for Intermediate 28, Step C afforded the title compound as a white powder. LC/MS 204.0 (M+1).
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US07388019B2 |
| Quelldatensatz | uspto-grants-2008_06 |
| ORD ID | ord-cc45c23990ba456899627ba7fa8afba1 |
| Quellennotiz | uspto-grants-2008_06 |