HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
HRID 13292Erstellt: 25. Oktober 2026
Potassium Carbonate → 5-(2-Cyano-phenoxy)-4-(6-methanesulfonyl-pyridin-3-yloxy)-2-nitro-phenylamine
https://huagongshe.com/reaction/13292
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|
| Edukt | Potassium Carbonate | HCID 11430 | — |
| Edukt | 2-Hydroxybenzonitrile | HCID 11907 | — |
| Edukt | N-methyl-2-pyrrolidone | HCID 13387 | — |
| Edukt | 5-Fluoro-4-(6-methanesulfonyl-pyridin-3-yloxy)-2-nitro-phenylamine | HCID 23145333 | — |
| Lösungsmittel | Water | HCID 962 | — |
| Produkt | 5-(2-Cyano-phenoxy)-4-(6-methanesulfonyl-pyridin-3-yloxy)-2-nitro-phenylamine | HCID 23145776 | — |
Reaktionsschritte
60 mg of 2-hydroxy-benzonitrile and 70 mg of potassium carbonate were added to an N-methylpyrrolidinone (2 ml) solution of 150 mg of 5-fluoro-4-(6-methanesulfonyl-pyridin-3-yloxy)-2-nitro-phenylamine obtained in (step 3), and the reaction liquid was stirred at 90° C. for 5 hours. Water was added to the reaction liquid, and the deposit was taken out through filtration to obtain the entitled compound.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patentnummer | US07728025B2 |
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| Quelldatensatz | uspto-grants-2010_06 |
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| ORD ID | ord-2db017ca3f4142d080bb5cc0e86c3cf0 |
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| Quellennotiz | uspto-grants-2010_06 |
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