methyl pyrazine-2-carboximidate → HCID 23145437, Verbindung

HRID 13310

Reaktionsgleichung

Reaktionsgleichung von HRID 13310
[F:1][C:2]1[CH:35]=[CH:34][CH:33]=[CH:32][C:3]=1[O:4][C:5]1[C:19]([O:20][C:21]2[CH:22]=[N:23][C:24]([S:27]([CH2:30][CH3:31])(=[O:29])=[O:28])=[CH:25][CH:26]=2)=[CH:18][C:8]2[NH:9][C:10]([C:12]3[CH:17]=C[CH:15]=[CH:14][N:13]=3)=[N:11][C:7]=2[CH:6]=1.COC(C1C=NC=CN=1)=[NH:39]>>[F:1][C:2]1[CH:35]=[CH:34][CH:33]=[CH:32][C:3]=1[O:4][C:5]1[C:19]([O:20][C:21]2[CH:22]=[N:23][C:24]([S:27]([CH2:30][CH3:31])(=[O:28])=[O:29])=[CH:25][CH:26]=2)=[CH:18][C:8]2[NH:9][C:10]([C:12]3[CH:17]=[N:39][CH:15]=[CH:14][N:13]=3)=[N:11][C:7]=2[CH:6]=1

Komponenten

3

Edukt 2

HCID 470894methyl pyrazine-2-carboximidateHCID 113977045-(2-Fluoro-phenoxy)-2-pyridin-2-yl-6-(6-ethanesulfonyl-pyridin-3-yloxy)-1H-benzimidazole

Produkt 1

HCID 23145437HCID 23145437, Verbindung

Versuchsvorschrift

The entitled compound was obtained as a brown solid in the same method as in Example 205 or in accordance with the method or by combining it with an ordinary method but using 4-(2-fluoro-phenoxy)-5-(6-ethanesulfonyl-pyridin-3-yloxy)-benzene-1,2-diamine obtained in Example 223 and methylpyrazin-2-imidate.

Aufarbeitung

  1. customThe entitled compound was obtained as a brown solid in the same method as in Example 205 or in accordance with the method

Quellen und Nachweise

ORD-Eintrag
ord-d19c82f9ec2a49289d38b2d29f4086c9
Quelldatensatz
uspto-grants-2010_06
Patentnummer
US07728025B2

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