HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
3-Amino-2,3,4,5-tetrahydro-1H-benzazepin-2-one → 3-(N'-(3,5-Difluorophenylacetyl)-L-alaninyl)amino-1,3,4,5-tetrahydro-2H-1-benzazepin-2-one
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 3-Amino-2,3,4,5-tetrahydro-1H-benzazepin-2-one | HCID 4434433 | — |
| Edukt | (2S)-2-[[2-(3,5-difluorophenyl)acetyl]amino]propanoic acid | HCID 12135350 | — |
| Produkt | 3-(N'-(3,5-Difluorophenylacetyl)-L-alaninyl)amino-1,3,4,5-tetrahydro-2H-1-benzazepin-2-one | HCID 10294459 | — |
Reaktionsschritte
Following General Procedure A above using N-(3,5-difluorophenylacetyl)-L-alanine (Example B) and 3-amino-1,3,4,5-tetrahydro-2H-1-benzazepin-2-one (General Procedure 6-B), the title compound was prepared. The reaction was monitored by tlc on silica gel (Rf=0.15 in 12% methanol/dichloromethane) and purification was by flash chromatography using 12% methanol/dichloromethane as the eluant.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US07390801B2 |
| Quelldatensatz | uspto-grants-2008_06 |
| ORD ID | ord-aab835957cbe4552bd60b080c6d98579 |
| Quellennotiz | uspto-grants-2008_06 |