HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
HRID 13326Erstellt: 23. Oktober 2026
Dimethylformamide → N-(4-benzyloxy-5-(2-fluorophenoxy)-2-nitrophenyl)pyrazinecarboxamide
https://huagongshe.com/de/reaction/13326
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|
| Edukt | Dimethylformamide | HCID 6228 | — |
| Edukt | 2-Fluorophenol | HCID 9707 | — |
| Edukt | Potassium Carbonate | HCID 11430 | — |
| Edukt | N-(4-benzyloxy-5-fluoro-2-nitrophenyl)pyrazinecarboxamide | HCID 23145743 | — |
| Lösungsmittel | Water | HCID 962 | — |
| Produkt | N-(4-benzyloxy-5-(2-fluorophenoxy)-2-nitrophenyl)pyrazinecarboxamide | HCID 23145658 | — |
Reaktionsschritte
0.54 ml of 2-fluorophenol and 2.53 g of potassium carbonate were added to a dimethylformamide (16 ml) solution of 2.14 g of N-(4-benzyloxy-5-fluoro-2-nitrophenyl)pyrazinecarboxamide, and the reaction liquid was stirred at 90° C. for 5 hours, and then water was added to it. The resulting deposit was taken out through filtration to obtain the entitled compound as a yellow solid.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patentnummer | US07728025B2 |
|---|
| Quelldatensatz | uspto-grants-2010_06 |
|---|
| ORD ID | ord-76da9412acef46d08b316ba9c7c4c87c |
|---|
| Quellennotiz | uspto-grants-2010_06 |
|---|