HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
2-Chloro-4-fluorobenzonitrile → n-(3-Chloro-4-cyanophenyl)alanine iso-butyl ester
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 2-Chloro-4-fluorobenzonitrile | HCID 109000 | — |
| Edukt | 2-Methylpropyl 2-aminopropanoate hydrochloride | HCID 86200109 | — |
| Produkt | n-(3-Chloro-4-cyanophenyl)alanine iso-butyl ester | HCID 53791223 | — |
Reaktionsschritte
Following General Procedure AP above and using 2-chloro-4-fluorobenzonitrile (Aldrich) and D,L-alanine iso-butyl ester hydrochloride (from Example AA above), the title compound was prepared. The product was recovered by column chromatography on silica gel using 1:5 EtOAc/hexanes as the eluant.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US07390801B2 |
| Quelldatensatz | uspto-grants-2008_06 |
| ORD ID | ord-b417a860cdef47898322d20ece20b974 |
| Quellennotiz | uspto-grants-2008_06 |