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HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
HRID 133357Erstellt: 25. Oktober 2026

1-Naphthaleneacetic Acid → N-[(1-naphthyl)acetyl]-L-alanine Iso-butyl Ester

https://huagongshe.com/reaction/133357

Reaktionsgleichung

Beteiligte Stoffe

RolleNameHCIDEinwaage
Edukt1-Naphthaleneacetic AcidHCID 6862—
Edukt2-Methylpropyl (2S)-2-aminopropanoate hydrochlorideHCID 86584981—
ProduktN-[(1-naphthyl)acetyl]-L-alanine Iso-butyl EsterHCID 15481767—

Reaktionsschritte

Following General Procedure BB and using 1-naphthylacetic acid (Aldrich) and L-alanine iso-butyl ester hydrochloride (from Example BB above), the title compound was prepared as a solid having a melting point of 69°-73° C. The reaction was monitored by tlc on silica gel and purification was by extraction with Et2O followed by washes with aqueous K2CO3 and aqueous HCl.

Herkunft & Nachweise

DOI10.6084/m9.figshare.5104873.v1
PatentnummerUS07390801B2
Quelldatensatzuspto-grants-2008_06
ORD IDord-f366a7b2609348ada18bd80849b1b55b
Quellennotizuspto-grants-2008_06