HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
1-Methyl-3-hydroxypyridine-2-one → 5-(1-Methyl-2-oxo-1,2-dihydro-pyridin-3-yloxy)-6-(4-methanesulfonyl-phenoxy)-2-pyridin-2-yl-1H-benzimidazole
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 1-Methyl-3-hydroxypyridine-2-one | HCID 88026 | — |
| Edukt | 5-(2-Ethoxycarbonyl-phenoxy)-6-(4-methanesulfonyl-phenoxy)-2-pyridin-2-yl-1H-benzimidazole | HCID 23145140 | — |
| Produkt | 5-(1-Methyl-2-oxo-1,2-dihydro-pyridin-3-yloxy)-6-(4-methanesulfonyl-phenoxy)-2-pyridin-2-yl-1H-benzimidazole | HCID 23145395 | — |
Reaktionsschritte
The entitled compound was obtained as a brown solid in the same method as in Example 14 or in accordance with the method or by combining it with an ordinary method but using 5-fluoro-4-(4-methanesulfonyl-phenoxy)-2-nitro-phenylamine obtained in Example 14 and 1-methyl-2-oxo-1,2-dihydro-pyridin-3-ol.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US07728025B2 |
| Quelldatensatz | uspto-grants-2010_06 |
| ORD ID | ord-3b99a0b0c8f64e1e85c662db1bbbab56 |
| Quellennotiz | uspto-grants-2010_06 |