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HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
HRID 13366Erstellt: 26. Oktober 2026

(S)-Pyrrolidine-2-carboxamide monohydrochloride → (2S)-1-(6-(4-methanesulfonyl-phenoxy)-2-pyridin-2-yl-3H-benzimidazol-5-yl)-pyrrolidine-2-carboxamide

https://huagongshe.com/reaction/13366

Reaktionsgleichung

Beteiligte Stoffe

RolleNameHCIDEinwaage
Edukt(S)-Pyrrolidine-2-carboxamide monohydrochlorideHCID 12707183—
Edukt5-(2-Ethoxycarbonyl-phenoxy)-6-(4-methanesulfonyl-phenoxy)-2-pyridin-2-yl-1H-benzimidazoleHCID 23145140—
Produkt(2S)-1-(6-(4-methanesulfonyl-phenoxy)-2-pyridin-2-yl-3H-benzimidazol-5-yl)-pyrrolidine-2-carboxamideHCID 67482658—

Reaktionsschritte

The entitled compound was obtained as a pale yellow solid in the same method as in Example 15 or in accordance with the method or by combining it with an ordinary method but using 5-fluoro-4-(4-methanesulfonyl-phenoxy)-2-nitro-phenylamine obtained in Example 14, and L-prolinamide hydrochloride.

Herkunft & Nachweise

DOI10.6084/m9.figshare.5104873.v1
PatentnummerUS07728025B2
Quelldatensatzuspto-grants-2010_06
ORD IDord-709c9c22110f417db56b65f4de5fc2ca
Quellennotizuspto-grants-2010_06