HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
3-Fluoropyrrolidine → 6-((3R)-3-fluoro-pyrrolidin-1-yl)-5-(4-methanesulfonyl-phenoxy)-2-pyridin-2-yl-1H-benzimidazole
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 3-Fluoropyrrolidine | HCID 2759163 | — |
| Edukt | 5-(2-Ethoxycarbonyl-phenoxy)-6-(4-methanesulfonyl-phenoxy)-2-pyridin-2-yl-1H-benzimidazole | HCID 23145140 | — |
| Produkt | 6-((3R)-3-fluoro-pyrrolidin-1-yl)-5-(4-methanesulfonyl-phenoxy)-2-pyridin-2-yl-1H-benzimidazole | HCID 67482926 | — |
Reaktionsschritte
The entitled compound was obtained as a yellow oily substance in the same method as in Example 15 or in accordance with the method or by combining it with an ordinary method but using 5-fluoro-4-(4-methanesulfonyl-phenoxy)-2-nitro-phenylamine obtained in Example 14, and (R)-3-fluoropyrrolidine.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US07728025B2 |
| Quelldatensatz | uspto-grants-2010_06 |
| ORD ID | ord-358a766059a04eb4bdccfca5422ab0f0 |
| Quellennotiz | uspto-grants-2010_06 |