Dabco → 1-[4-(4-{3-[1-(4-Fluorophenyl)-2-(4-methoxyphenyl)-4-oxoazetidin-3-yl]-1-hydroxypropyl}-phenoxymethyl)-benzyl]-4-aza-1-azoniabicyclo[2.2.2]octane bromide

Beteiligte Stoffe

Rolle	Name	HCID	Einwaage
Edukt	Dabco	HCID 9237	—
Edukt	3-{3-[4-(4-Bromomethylbenzyloxy)-phenyl]-3-hydroxypropyl}-1-(4-fluorophenyl)4-(4-methoxyphenyl)-azetidin-2-one	HCID 21083178	—
Lösungsmittel	Toluene	HCID 1140	—
Produkt	1-[4-(4-{3-[1-(4-Fluorophenyl)-2-(4-methoxyphenyl)-4-oxoazetidin-3-yl]-1-hydroxypropyl}-phenoxymethyl)-benzyl]-4-aza-1-azoniabicyclo[2.2.2]octane bromide	HCID 21083161	—

Reaktionsschritte

Compound (29) and DABCO were dissolved in toluene and reacted analogously to Example IV, giving the product (30) as a colorless solid of molecular weight 716.70 (C39H43BrFN3O4); MS (ESI): 636.3 (MH+).

Herkunft & Nachweise

DOI	10.6084/m9.figshare.5104873.v1
Patentnummer	US07390790B2
Quelldatensatz	uspto-grants-2008_06
ORD ID	ord-cffd8ce0ce1c4ff69a8ddbbbdd7581f6
Quellennotiz	uspto-grants-2008_06