2,3-Difluorobenzonitrile → 3-Fluoro-4-(2-fluoro-6-cyano-phenoxy)-phenylamine

HRID 13376

Reaktionsgleichung

Reaktionsgleichung von HRID 13376
[F:1][C:2]1[CH:3]=[C:4]([NH:9]C(=O)OC(C)(C)C)[CH:5]=[CH:6][C:7]=1[OH:8].[F:17][C:18]1[CH:23]=[CH:22][CH:21]=[C:20]([C:24]#[N:25])[C:19]=1F>>[F:1][C:2]1[CH:3]=[C:4]([NH2:9])[CH:5]=[CH:6][C:7]=1[O:8][C:19]1[C:20]([C:24]#[N:25])=[CH:21][CH:22]=[CH:23][C:18]=1[F:17]

Komponenten

3

Edukt 2

HCID 889352,3-DifluorobenzonitrileHCID 11708410tert-Butyl (3-Fluoro-4-hydroxyphenyl)carbamate

Produkt 1

HCID 231455073-Fluoro-4-(2-fluoro-6-cyano-phenoxy)-phenylamine

Versuchsvorschrift

The entitled compound was obtained in the same method as in Example 221 (step 1) or in accordance with the method or by combining it with an ordinary method but using tert-butyl (3-fluoro-4-hydroxy-phenyl)-carbamate obtained in Example 196 (step 1) and 1,2-difluoro-3-cyano-benzene.

Aufarbeitung

  1. customThe entitled compound was obtained in the same method as in Example 221 (step 1) or in accordance with the method

Quellen und Nachweise

ORD-Eintrag
ord-414d8a4d43ff49a59592db1cbfed2ad3
Quelldatensatz
uspto-grants-2010_06
Patentnummer
US07728025B2

Verknüpfte Notizen

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