HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Ethanol → HCID 178513350, Verbindung
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Ethanol | HCID 702 | — |
| Edukt | Hydroxylamine | HCID 787 | — |
| Edukt | 5-(2-Fluoro-phenoxy)-2-pyrazin-2-yl-6-(6-cyano-pyridin-3-yloxy)-1H-benzimidazole | HCID 23145142 | — |
| Produkt | HCID 178513350 | HCID 178513350 | — |
Reaktionsschritte
0.5 ml of hydroxyamine (50% aqueous solution) was added to an ethanol (0.5 ml) solution of 6.0 mg of 5-(2-fluoro-phenoxy)-2-pyrazin-2-yl-6-(6-cyano-pyridin-3-yloxy)-1H-benzimidazole obtained in Example 252, and the reaction liquid was stirred at room temperature for 3 hours. Then, the solvent was evaporated away under reduced pressure to obtain the entitled compound as a pale yellow solid.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US07728025B2 |
| Quelldatensatz | uspto-grants-2010_06 |
| ORD ID | ord-b65b6ca0e7964ffe9e5e5a80eef06ad7 |
| Quellennotiz | uspto-grants-2010_06 |