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HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
HRID 13378Erstellt: 23. Oktober 2026

Ethanol → HCID 178513350, Verbindung

https://huagongshe.com/de/reaction/13378

Reaktionsgleichung

Beteiligte Stoffe

RolleNameHCIDEinwaage
EduktEthanolHCID 702—
EduktHydroxylamineHCID 787—
Edukt5-(2-Fluoro-phenoxy)-2-pyrazin-2-yl-6-(6-cyano-pyridin-3-yloxy)-1H-benzimidazoleHCID 23145142—
ProduktHCID 178513350HCID 178513350—

Reaktionsschritte

0.5 ml of hydroxyamine (50% aqueous solution) was added to an ethanol (0.5 ml) solution of 6.0 mg of 5-(2-fluoro-phenoxy)-2-pyrazin-2-yl-6-(6-cyano-pyridin-3-yloxy)-1H-benzimidazole obtained in Example 252, and the reaction liquid was stirred at room temperature for 3 hours. Then, the solvent was evaporated away under reduced pressure to obtain the entitled compound as a pale yellow solid.

Herkunft & Nachweise

DOI10.6084/m9.figshare.5104873.v1
PatentnummerUS07728025B2
Quelldatensatzuspto-grants-2010_06
ORD IDord-b65b6ca0e7964ffe9e5e5a80eef06ad7
Quellennotizuspto-grants-2010_06