HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
2,4-Difluorobenzonitrile → 4-(2-Cyano-5-fluoro-phenoxy)-6-(6-ethanesulfonyl-pyridin-3-yloxy)-2-pyrazin-2-yl-1H-benzimidazole
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 2,4-Difluorobenzonitrile | HCID 77545 | — |
| Edukt | 4-(2-Cyano-6-fluoro-phenoxy)-6-(6-ethanesulfonyl-pyridin-3-yloxy)-2-pyrazin-2-yl-1H-benzimidazole | HCID 11318284 | — |
| Produkt | 4-(2-Cyano-5-fluoro-phenoxy)-6-(6-ethanesulfonyl-pyridin-3-yloxy)-2-pyrazin-2-yl-1H-benzimidazole | HCID 23145774 | — |
Reaktionsschritte
The entitled compound was obtained in the same method as in Example 438 (step 2) or in accordance with the method or by combining it with an ordinary method but using 4-hydroxy-6-(6-ethanesulfonyl-pyridin-3-yloxy)-2-pyrazin-2-yl-1H-benzimidazole obtained in Example 442 and 2,4-difluoro-benzonitrile.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US07728025B2 |
| Quelldatensatz | uspto-grants-2010_06 |
| ORD ID | ord-66a93e76712942c3813a3be8630cacbb |
| Quellennotiz | uspto-grants-2010_06 |