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HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
HRID 13416Erstellt: 23. Oktober 2026

2-Methyl-5-hydroxypyridine → 6-(1-Acetyl-5-methylpyrrolidin-2-yl)-5-((6-methylpyridin-3-yl)oxy)-2-pyridin-2-yl-1H-benzimidazole

https://huagongshe.com/de/reaction/13416

Reaktionsgleichung

Beteiligte Stoffe

RolleNameHCIDEinwaage
Edukt2-Methyl-5-hydroxypyridineHCID 14275—
EduktN-(4-(1-acetyl-5-methylpyrrolidin-2-yl)-5-fluoro-2-nitrophenyl)pyridine-2-carboxamideHCID 23145552—
Produkt6-(1-Acetyl-5-methylpyrrolidin-2-yl)-5-((6-methylpyridin-3-yl)oxy)-2-pyridin-2-yl-1H-benzimidazoleHCID 23145192—

Reaktionsschritte

The entitled compound was obtained as a pale yellow solid in the same method as in Example 338 (step 5) or in accordance with the method or by combining it with an ordinary method but using N-(4-(1-acetyl-5-methylpyrrolidin-2-yl)-5-fluoro-2-nitrophenyl)pyridine-2-carboxamide obtained in Example 545 and 6-methylpyridin-3-ol.

Herkunft & Nachweise

DOI10.6084/m9.figshare.5104873.v1
PatentnummerUS07728025B2
Quelldatensatzuspto-grants-2010_06
ORD IDord-e9a8116868f6419094ed6c0955c19366
Quellennotizuspto-grants-2010_06