HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
4-Bromoaniline → (4-Bromophenyl)(5-methoxybenzoxazol-2-yl)amine
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 4-Bromoaniline | HCID 7807 | — |
| Edukt | Diisopropylethylamine | HCID 81531 | — |
| Edukt | 2-Chloro-5-methoxy-1,3-benzoxazole | HCID 11819712 | — |
| Lösungsmittel | Dimethylformamide | HCID 6228 | — |
| Produkt | (4-Bromophenyl)(5-methoxybenzoxazol-2-yl)amine | HCID 22040817 | — |
Reaktionsschritte
The mixture containing 2-chloro-5-methoxybenzoxazole (1 eq), 4-bromoaniline (2 eq) and diisopropylethylamine was refluxed in dimethylformamide. The resultant mixture was concentrated and partitioned between ethyl acetate and water. The organic layer was washed with brine and dried. Purification on silica gel gave (4-bromophenyl)(5-methoxybenzoxazol-2-yl)amine. MS: MH+=318
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US07728010B2 |
| Quelldatensatz | uspto-grants-2010_06 |
| ORD ID | ord-9bac4797f8dc4d1cae695a5979e23f2d |
| Quellennotiz | uspto-grants-2010_06 |