2-Methylbenzoic acid → 2-Methyl-N-[4-[(2,3,4,5-tetrahydro-5-oxo-1H-1-benzazepin-1-yl)carbonyl]phenyl]benzamide

HRID 1348

Reaktionsgleichung

Reaktionsgleichung von HRID 1348
[CH3:1][C:2]1[CH:10]=[CH:9][CH:8]=[CH:7][C:3]=1[C:4]([OH:6])=O.[NH2:11][C:12]1[CH:31]=[CH:30][C:15]([C:16]([N:18]2[C:24]3[CH:25]=[CH:26][CH:27]=[CH:28][C:23]=3[C:22](=[O:29])[CH2:21][CH2:20][CH2:19]2)=[O:17])=[CH:14][CH:13]=1>>[CH3:1][C:2]1[CH:10]=[CH:9][CH:8]=[CH:7][C:3]=1[C:4]([NH:11][C:12]1[CH:13]=[CH:14][C:15]([C:16]([N:18]2[C:24]3[CH:25]=[CH:26][CH:27]=[CH:28][C:23]=3[C:22](=[O:29])[CH2:21][CH2:20][CH2:19]2)=[O:17])=[CH:30][CH:31]=1)=[O:6]

Komponenten

3

Edukt 2

HCID 83732-Methylbenzoic acidHCID 107078741-(4-aminobenzoyl)-2,3,4,5-tetrahydro-1H-1-benzazepin-5-one

Produkt 1

HCID 108108812-Methyl-N-[4-[(2,3,4,5-tetrahydro-5-oxo-1H-1-benzazepin-1-yl)carbonyl]phenyl]benzamide

Versuchsvorschrift

Using o-methylbenzoic acid and 1-(4-aminobenzoyl)-2,3,4,5-tetrahydro-1H-1-benzazepin-5-one as starting materials, the procedure of Reference Example 3 was repeated to obtain 2-methyl-4'-[(5-oxo-2,3,4,5-tetrahydro-1H-1-benzazepin-1-yl)carbonyl]benzanilide.

Quellen und Nachweise

ORD-Eintrag
ord-23a39ece3a4041d69c341d884e898380
Quelldatensatz
uspto-grants-1998_03
Patentnummer
US05723606

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