2-Amino-1-(naphthalen-2-yl)ethan-1-ol → (2S,4EZ)-N-[(2RS)-2-hydroxy-2-(2-naphthlyl)ethyl]-1-[(2'-methoxy[1,1'-biphenyl]4-yl)carbonyl]-4-(methoxyimino)-2-pyrrolidinecarboxamide

Beteiligte Stoffe

Reaktionsschritte

Following the general method as outlined in Example 22, starting from (2S,4EZ)-1-(tert-butoxycarbonyl)-4-(methoxyimino)-2-pyrrolidinecarboxylic acid, 2′-methoxy[1,1′-biphenyl]-4-carboxylic acid, and (1RS)-2-amino-1-(2-naphthyl)ethanol, the title compound was obtained in 67% purity by HPLC. MS(ESI+): m/z=538.

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