Stannous Chloride → 2-Isopropyl-5H-dibenzo[b,e][1,4]diazepin-11-ylamine hydrochloride

Beteiligte Stoffe

Reaktionsbedingungen

Reaktionsschritte

Combine 5-isopropyl-2-(2-nitro-phenylamino)-benzonitrile (4.54 g, 16.1 mmol) and tin (II) chloride (10.92 g, 48.4 mmol) in 65.0 mL of 5N HCl solution and 65.0 mL of ethanol. Heat this mixture at 86° C. for 18 hours. Chilling the mixture precipitates the title compound as 4.22 g of a yellow solid: mp>250° C.; mass spectrum (ion spray): m/z=252 (M+1).

Herkunft & Nachweise