HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
4-Piperidineethanol → 2-[1-(6-Chloro-2-quinolyl)-4-piperidyl]ethanol
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 4-Piperidineethanol | HCID 73953 | — |
| Edukt | 2,6-Dichloroquinoline | HCID 607502 | — |
| Produkt | 2-[1-(6-Chloro-2-quinolyl)-4-piperidyl]ethanol | HCID 21096926 | — |
Reaktionsschritte
The process is performed as described in Example 4 (step 4.1). Starting with 2 g (10.10 mmol) of 2,6-dichloroquinoline and 1.44 g (11.10 mmol) of 2-(4-piperidyl)ethanol, and after chromatography on silica gel, eluting with a 98/2 mixture of dichloromethane and methanol, 2.54 g of pure product are obtained in the form of a white solid.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US07214798B2 |
| Quelldatensatz | uspto-grants-2007_05 |
| ORD ID | ord-3a92dc86b6ff4b31a1a564e77d29ddeb |
| Quellennotiz | uspto-grants-2007_05 |