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HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
HRID 1350573Erstellt: 25. Oktober 2026

4-Piperidineethanol → 2-[1-(6-Chloro-2-quinolyl)-4-piperidyl]ethanol

https://huagongshe.com/reaction/1350573

Reaktionsgleichung

Beteiligte Stoffe

RolleNameHCIDEinwaage
Edukt4-PiperidineethanolHCID 73953—
Edukt2,6-DichloroquinolineHCID 607502—
Produkt2-[1-(6-Chloro-2-quinolyl)-4-piperidyl]ethanolHCID 21096926—

Reaktionsschritte

The process is performed as described in Example 4 (step 4.1). Starting with 2 g (10.10 mmol) of 2,6-dichloroquinoline and 1.44 g (11.10 mmol) of 2-(4-piperidyl)ethanol, and after chromatography on silica gel, eluting with a 98/2 mixture of dichloromethane and methanol, 2.54 g of pure product are obtained in the form of a white solid.

Herkunft & Nachweise

DOI10.6084/m9.figshare.5104873.v1
PatentnummerUS07214798B2
Quelldatensatzuspto-grants-2007_05
ORD IDord-3a92dc86b6ff4b31a1a564e77d29ddeb
Quellennotizuspto-grants-2007_05