N-bromobutanimide → 3-(Bromomethyl)phenyl acetate

HRID 1351087

Reaktionsgleichung

Reaktionsgleichung von HRID 1351087
[C:1]([O:4][C:5]1[CH:6]=[C:7]([CH3:11])[CH:8]=[CH:9][CH:10]=1)(=[O:3])[CH3:2].[Br:12]N1C(=O)CCC1=O>ClC(Cl)(Cl)Cl.N(C(C)(C)C#N)=NC(C)(C)C#N>[C:1]([O:4][C:5]1[CH:10]=[CH:9][CH:8]=[C:7]([CH2:11][Br:12])[CH:6]=1)(=[O:3])[CH3:2]

Komponenten

5

Edukt 2

HCID 67184N-bromobutanimideHCID 67406Cresatin

Produkt 1

HCID 64220753-(Bromomethyl)phenyl acetateAusbeute 100,4 %

Reagenzien, Katalysatoren, Lösungsmittel 2

HCID 6547AzobisisobutyronitrileKatalysatorHCID 5943Carbon TetrachlorideLösungsmittel

Versuchsvorschrift

A suspension of m-tolyl acetate (583 mg), N-bromosuccinimide (691 mg) and α,α′-azobis(isobutyronitrile) (13 mg) in tetrachloromethane (10 mL) was refluxed for 1 hour. The reaction mixture was cooled to room temperature, and the insoluble material was removed by filtration. The filtrate was concentrated to give the title compound (893 mg).

Aufarbeitung

  1. temperaturewas refluxed for 1 hour
  2. customthe insoluble material was removed by filtration
  3. concentrationThe filtrate was concentrated

Quellen und Nachweise

ORD-Eintrag
ord-d803bf4dc0984eeba3872c4297924e16
Quelldatensatz
uspto-grants-2007_05
Patentnummer
US07217697B2

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