(2-(4-Fluorophenyl)ethyl)(methyl)amine → 6-Methyl-7-oxo-4,5,6,7-tetrahydrobenzo[b]thiophene-3-sulfonic acid[2-(4-fluorophenyl)ethyl]-methyl-amide

HRID 1351286Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1351286
[CH3:1][CH:2]1[C:14](=[O:15])[C:6]2[S:7][CH:8]=[C:9]([S:10](Cl)(=[O:12])=[O:11])[C:5]=2[CH2:4][CH2:3]1.[F:16][C:17]1[CH:22]=[CH:21][C:20]([CH2:23][CH2:24][NH:25][CH3:26])=[CH:19][CH:18]=1>>[F:16][C:17]1[CH:18]=[CH:19][C:20]([CH2:23][CH2:24][N:25]([CH3:26])[S:10]([C:9]2[C:5]3[CH2:4][CH2:3][CH:2]([CH3:1])[C:14](=[O:15])[C:6]=3[S:7][CH:8]=2)(=[O:12])=[O:11])=[CH:21][CH:22]=1

Komponenten

3

Edukt 2

HCID 120234(2-(4-Fluorophenyl)ethyl)(methyl)amineHCID 210986726-Methyl-7-oxo-4,5,6,7-tetrahydrobenzo[b]thiophene-3-sulfonyl chloride

Produkt 1

HCID 210986706-Methyl-7-oxo-4,5,6,7-tetrahydrobenzo[b]thiophene-3-sulfonic acid[2-(4-fluorophenyl)ethyl]-methyl-amide

Versuchsvorschrift

From 6-methyl-7-oxo-4,5,6,7-tetrahydrobenzo[b]thiophene-3-sulfonyl chloride (the compound of Preparation Example 13) (140 mg) and [2-(4-fluorophenyl)ethyl]methylamine (the compound of Preparation Example 14) (98 mg), the title compound (152 mg) was obtained as an orange oily substance, in the same way as Preparation Example 41.

Aufarbeitung

  1. customthe compound of Preparation Example 14) (98 mg)

Quellen und Nachweise

ORD-Eintrag
ord-a71681e5cb1441d9880ce2217c7aaf53
Quelldatensatz
uspto-grants-2007_05
Patentnummer
US07217723B2

Notizen zur Reaktion

Wird geladen…