Ethyl 2-(4-bromophenyl)-2-methylpropanoate → 2-Methyl-2-(1,3-thiazol-2-yl)propanoic acid

Reaktionsgleichung

[CH3:1][C:2]([C:9]1[S:10][CH:11]=[CH:12][N:13]=1)([CH3:8])[C:3]([O:5]CC)=[O:4].BrC1C=CC(C(C)(C)C(OCC)=O)=CC=1>>[CH3:8][C:2]([C:9]1[S:10][CH:11]=[CH:12][N:13]=1)([CH3:1])[C:3]([OH:5])=[O:4]

Komponenten

Edukt 2

HCID 11277257Ethyl 2-(4-bromophenyl)-2-methylpropanoate

HCID 21099803Ethyl 2-methyl-2-(thiazol-2-yl)propanoate

Produkt 1

HCID 210997222-Methyl-2-(1,3-thiazol-2-yl)propanoic acid

Versuchsvorschrift

The title compound was prepared according to the method of Example 22B substituting the product of Example 44D for the product of Example 22A.

Quellen und Nachweise

ORD-Eintrag: ord-eb42f3d3eedf46038aa0bd2c793ab33d
Quelldatensatz: uspto-grants-2007_05
DOI: 10.6084/m9.figshare.5104873.v1
Patentnummer: US07217838B2

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