HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
1-(1-Naphthyl)ethylamine → (2S)-2-methoxy-3-{4-[(1-naphthalen-1-yl-ethylcarbamoyl)-methoxy]-phenyl}-propionic acid
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 1-(1-Naphthyl)ethylamine | HCID 98089 | — |
| Edukt | (2S,1R)-2-ethoxy-3-(4-{1-[2-(4-phenoxy-phenyl)-ethylcarbamoyl]-ethoxy}-phenyl)propionic acid | HCID 9847886 | — |
| Edukt | (2S)-3-(4-carboxymethoxy-phenyl)-2-methoxy-propionic acid ethyl ester | HCID 58864673 | — |
| Produkt | (2S)-2-methoxy-3-{4-[(1-naphthalen-1-yl-ethylcarbamoyl)-methoxy]-phenyl}-propionic acid | HCID 69420348 | — |
Reaktionsschritte
The title compound was prepared from (2S)-3-(4-carboxymethoxy-phenyl)-2-methoxy-propionic acid ethyl ester (PREPARATION 3, step 2) and 1-naphthalen-1-yl-ethylamine via the same procedure used for the preparation of (2S,1R)-2-ethoxy-3-(4-{1-[2-(4-phenoxy-phenyl)-ethylcarbamoyl]-ethoxy}-phenyl)-propionic acid (Example 1, step 3) to produce a colorless oil. MS (ES) for C24H25NO5 [M+H]+: 408.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US07220880B2 |
| Quelldatensatz | uspto-grants-2007_05 |
| ORD ID | ord-f349263cc0794ed5983803b548ea31be |
| Quellennotiz | uspto-grants-2007_05 |