2-(Benzenesulfonyl)-3-phenyloxaziridine → 2-(Methylsulfinyl)pyrimidine

HRID 1355683

Reaktionsgleichung

Reaktionsgleichung von HRID 1355683
[CH3:1][S:2][C:3]1[N:8]=[CH:7][CH:6]=[CH:5][N:4]=1.C1(C2[O:17]N2S(C2C=CC=CC=2)(=O)=O)C=CC=CC=1>ClCCl>[CH3:1][S:2]([C:3]1[N:8]=[CH:7][CH:6]=[CH:5][N:4]=1)=[O:17]

Komponenten

4

Edukt 2

HCID 3204052-(Benzenesulfonyl)-3-phenyloxaziridineHCID 5227722-(Methylsulfanyl)pyrimidine

Produkt 1

HCID 114008322-(Methylsulfinyl)pyrimidine

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 6344DichloromethaneLösungsmittel

Versuchsvorschrift

The methylsulfanyl-pyrimidine compound of formula (83) is reacted with an oxidising agent, preferably 3-phenyl-2-(phenylsulfonyl)oxaziridine, in an organic solvent, preferably dichloromethane, at room temperature. The product of formula (84), a methanesulfinyl-pyrimidine derivative, is isolated by conventional means, and preferably reacted in the next step without further purification. The product of formula (84) may, however, be additionally purified by means of chromatography or recrystallisation.

Quellen und Nachweise

ORD-Eintrag
ord-224b15c6ee9741c48c8a184c2ab8484f
Quelldatensatz
uspto-grants-2003_07
Patentnummer
US06586441B2

Verknüpfte Notizen

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