Triethyl orthoacetate → HCID 10224551, Verbindung
Reaktionsgleichung
[F:1][C:2]1[CH:7]=[CH:6][C:5]([CH:8]2[N:12]([S:13]([C:16]3[CH:21]=[CH:20][C:19]([CH3:22])=[CH:18][CH:17]=3)(=[O:15])=[O:14])[CH:11]([CH2:23][CH2:24][C:25]([NH:27][NH2:28])=[O:26])[CH2:10][CH2:9]2)=[CH:4][CH:3]=1.[C:29](OCC)(OCC)(OCC)[CH3:30]>>[F:1][C:2]1[CH:7]=[CH:6][C:5]([CH:8]2[N:12]([S:13]([C:16]3[CH:21]=[CH:20][C:19]([CH3:22])=[CH:18][CH:17]=3)(=[O:14])=[O:15])[CH:11]([CH2:23][CH2:24][C:25]3[O:26][C:29]([CH3:30])=[N:28][N:27]=3)[CH2:10][CH2:9]2)=[CH:4][CH:3]=1Komponenten
3
Versuchsvorschrift
The title compound, light yellow oil, MS: m/e=430.2 (M+H+), was prepared in accordance with the general method of example 127 from (2RS,5SR)-3-[5-(4-fluoro-phenyl)-1-(toluene-4-sulfonyl)-pyrrolidin-2-yl]-propionic acid hydrazide and triethyl orthoacetate.
Quellen und Nachweise
- ORD-Eintrag
- ord-a2c1c6a4330c4021b28acc874b23ed3b
- Quelldatensatz
- uspto-grants-2003_07