Ethanol → HCID 9855924, Verbindung

HRID 1358543Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1358543
[C:1]([C:4]1[CH2:5][CH2:6][O:7][C:8]2[CH:14]=[CH:13][CH:12]=[CH:11][C:9]=2[CH:10]=1)([OH:3])=[O:2].[CH2:15](O)[CH3:16]>S(=O)(=O)(O)O>[CH2:15]([O:2][C:1]([C:4]1[CH2:5][CH2:6][O:7][C:8]2[CH:14]=[CH:13][CH:12]=[CH:11][C:9]=2[CH:10]=1)=[O:3])[CH3:16]

Komponenten

4

Edukt 2

HCID 702EthanolHCID 11116823HCID 11116823, Verbindung

Produkt 1

HCID 9855924HCID 9855924, Verbindung

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 1118Sulfuric AcidLösungsmittel

Versuchsvorschrift

A mixture of 8.2 g (0.043 mol) of 2,3-dihydro-4-carboxybenzoxepine in 150 ml of ethanol and 5 ml of concentrated sulphuric acid is brought to reflux for 6 hours. The reaction mixture is subsequently concentrated under reduced pressure and the residue is taken up in water. The combined mixture is extracted with ethyl acetate. The organic phase is then washed with sodium bicarbonate and then with water and dried over anhydrous sodium sulphate before being concentrated under reduced pressure. 8.5 g of an orange oil are thus obtained.

Aufarbeitung

  1. temperatureto reflux for 6 hours
  2. concentrationThe reaction mixture is subsequently concentrated under reduced pressure
  3. extractionThe combined mixture is extracted with ethyl acetate
  4. washThe organic phase is then washed with sodium bicarbonate
  5. dry with materialwith water and dried over anhydrous sodium sulphate
  6. concentrationbefore being concentrated under reduced pressure

Quellen und Nachweise

ORD-Eintrag
ord-f478c6f1b4a94736b09a56fd719e7e3a
Quelldatensatz
uspto-grants-2003_07
Patentnummer
US06596758B1

Notizen zur Reaktion

Wird geladen…