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HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
HRID 1359103Erstellt: 26. Oktober 2026

1-(4-Nitrophenyl)-1H-imidazole → 4-(1H-imidazol-1-yl)aniline

https://huagongshe.com/reaction/1359103

Reaktionsgleichung

Beteiligte Stoffe

RolleNameHCIDEinwaage
Edukt1-(4-Nitrophenyl)-1H-imidazoleHCID 123155—
KatalysatorPalladiumHCID 23938—
LösungsmittelMethanolHCID 887—
Produkt4-(1H-imidazol-1-yl)anilineHCID 32016589%

Reaktionsschritte

1-(4-nitrophenyl)-1H-imidazole (4.4 g; 23.5 mmoles) is put in solution in anhydrous methanol (140 ml) and palladium on carbon (0.44 g) is added to the medium. The reaction medium is placed under hydrogen for 4 hours. The catalyst is filtered off and the solvent is evapored to dryness. The expected product is obtained in a virtually pure state with a yield of 89% (3.3 g).

Herkunft & Nachweise

DOI10.6084/m9.figshare.5104873.v1
PatentnummerUS06599903B2
Quelldatensatzuspto-grants-2003_07
ORD IDord-0a3fe43ce1a440809bf3fd89fef583d4
Quellennotizuspto-grants-2003_07