HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
1-(4-Nitrophenyl)-1H-imidazole → 4-(1H-imidazol-1-yl)aniline
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 1-(4-Nitrophenyl)-1H-imidazole | HCID 123155 | — |
| Katalysator | Palladium | HCID 23938 | — |
| Lösungsmittel | Methanol | HCID 887 | — |
| Produkt | 4-(1H-imidazol-1-yl)aniline | HCID 320165 | 89% |
Reaktionsschritte
1-(4-nitrophenyl)-1H-imidazole (4.4 g; 23.5 mmoles) is put in solution in anhydrous methanol (140 ml) and palladium on carbon (0.44 g) is added to the medium. The reaction medium is placed under hydrogen for 4 hours. The catalyst is filtered off and the solvent is evapored to dryness. The expected product is obtained in a virtually pure state with a yield of 89% (3.3 g).
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US06599903B2 |
| Quelldatensatz | uspto-grants-2003_07 |
| ORD ID | ord-0a3fe43ce1a440809bf3fd89fef583d4 |
| Quellennotiz | uspto-grants-2003_07 |