HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Flecainide → 2,2,2-Trifluoroethyl 2,5-bis(2,2,2-trifluoroethoxy)benzoate
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Flecainide | HCID 3356 | — |
| Edukt | 2,5-Dihydroxybenzoic acid | HCID 3469 | — |
| Edukt | 2,2,2-Trifluoroethyl perfluorobutylsulfonate | HCID 2777144 | — |
| Produkt | 2,2,2-Trifluoroethyl 2,5-bis(2,2,2-trifluoroethoxy)benzoate | HCID 11281014 | — |
Reaktionsschritte
Process for the synthesis of FLECAINIDE comprising the reaction between 2,5-dihydroxybenzoic acid with trifluoroethanol perfluorobutanesulphonate to give the intermediate trifluoroethanol 2,5-bis-trifluoroethoxybenzoate, the reaction of said intermediate with 2-aminomethylpiperidine to give FLECAINIDE.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US06599922B2 |
| Quelldatensatz | uspto-grants-2003_07 |
| ORD ID | ord-362bf334465f4aea9bd4cda8d16c6c78 |
| Quellennotiz | uspto-grants-2003_07 |