Thionyl Chloride → 4-[2-(2-Chloromethyl-phenoxy)-ethyl]-morpholine hydrochloride

Beteiligte Stoffe

Reaktionsschritte

Thionyl chloride (5 mL, 2M in DCM) was added to a solution of [2-(2-morpholin-4-yl-ethoxy)-phenyl]-methanol (1.97 g, 8.3 mmol) in DCM (15 mL) at 0° C. The mixture was allowed to warm up to rt and stirred for 3 hours. The reaction was concentrated to give 4-[2-(2-chloromethyl-phenoxy)-ethyl]-morpholine hydrochloride.

Herkunft & Nachweise