N-(2-allyl-4-fluoro-phenyl)-acrylamide → HCID 57779786, Verbindung
Reaktionsgleichung
[CH2:1]([C:4]1[CH:9]=[C:8]([F:10])[CH:7]=[CH:6][C:5]=1[NH:11][C:12](=[O:15])[CH:13]=[CH2:14])C=C>ClCCl>[F:10][C:8]1[CH:7]=[CH:6][C:5]2[NH:11][C:12](=[O:15])[CH:13]=[CH:14][CH2:1][C:4]=2[CH:9]=1Komponenten
3
Edukt 1
Produkt 1
Reagenzien, Katalysatoren, Lösungsmittel 1
Versuchsvorschrift
A round-bottom flask containing the product from Step 2 (4.51 g, 21.9 mmol) was fitted with a stirbar and septa. Dichloromethane (800 mL) and Zhan catalyst I (0.735 g, 1.11 mmol) were added, and the resulting solution was stirred for 18 hours at room temperature. The reaction was then concentrated in vacuo and recrystallized from dichloromethane to give the desired product.
Aufarbeitung
- customwas fitted with a stirbar and septa
- concentrationThe reaction was then concentrated in vacuo
- customrecrystallized from dichloromethane
Quellen und Nachweise
- ORD-Eintrag
- ord-3acdda58df154d9586e72789305e7edf
- Quelldatensatz
- uspto-grants-2011_02
- Patentnummer
- US07888345B2
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