HCID 66936334, Verbindung → HCID 55288067, Verbindung
Reaktionsgleichung
[CH3:1][N:2]1[CH2:7][C@@H:6]([CH3:8])[N:5](CC2C=CC=CC=2)[CH2:4][C@H:3]1[CH3:16]>CO>[CH3:1][N:2]1[CH2:7][C@@H:6]([CH3:8])[NH:5][CH2:4][C@H:3]1[CH3:16]Komponenten
3
Edukt 1
Produkt 1
Reagenzien, Katalysatoren, Lösungsmittel 1
Versuchsvorschrift
(2R,5R)-1,2,5-Trimethyl-4-(phenylmethyl)piperazine (680 mg, 3.11 mmol) was dissolved in 50 mL of MeOH, degassed and placed under argon. 10% Pd/C (170 mg) was added, and the contents were thoroughly degassed and placed under a hydrogen balloon for approximately 3 hrs. The contents were then degassed and filtered through Celite, and the Celite pad was washed with DCM and MeOH. After 6.5 mL 1N HCl was added, the resulting filtrate was concentrated in vacuo to provide the hydrochloride salt of (2R,5R)-1,2,5-trimethylpiperazine (251 mg, 100%). LCMS: (M+H)+: 129.1.
Aufarbeitung
- custom