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HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
HRID 1366802Erstellt: 26. Oktober 2026

Diethyl Ether → 1-[5-(3-Chlorophenyl)-2-furyl]ethan-1-ol

https://huagongshe.com/reaction/1366802

Reaktionsgleichung

Beteiligte Stoffe

RolleNameHCIDEinwaage
EduktDiethyl EtherHCID 3283—
Edukt5-(3-Chlorophenyl)furfuralHCID 609822—
EduktHCID 178418689HCID 178418689—
LösungsmittelTetrahydrofuranHCID 8028—
Produkt1-[5-(3-Chlorophenyl)-2-furyl]ethan-1-olHCID 62498593—

Reaktionsschritte

To a solution of 5-(3-chlorophenyl)furan-2-carbaldehyde (1.0 equiv.) in THF at 0° C. was added MeMgBr in ether (3.0 equiv.) and stirred for 45 min. The reaction was quenched with water, diluted with ether and filtered through Celite. The organic layer was separated and washed with brine, dried over MgSO4, and concentrated to give the 1-[5-(3-chlorophenyl)-2-furyl]ethan-1-ol.

Herkunft & Nachweise

DOI10.6084/m9.figshare.5104873.v1
PatentnummerUS07893096B2
Quelldatensatzuspto-grants-2011_02
ORD IDord-ef510c6e17114ee2bb54dac234e3a116
Quellennotizuspto-grants-2011_02